Keratocystic odontogenic tumor related to nevoid basal cell carcinoma syndrome: clinicopathological study
نویسندگان
چکیده
1 Department of Stomatology, São Paulo University, São Paulo, SP, Brazil 2 Department of Stomatology, A. C. Camargo Hospital, São Paulo, SP, Brazil 3 Department of Oncogenetics, A. C. Camargo Hospital, São Paulo, SP, Brazil 4 Department of Anatomical Pathology, A. C. Camargo Hospital, São Paulo, SP, Brazil 5 Department of Stomatology, University of São Paulo, Department of Stomatology, A. C. Camargo Hospital, São Paulo, SP, Brazil
منابع مشابه
Keratocystic Odontogenic Tumor: Case Reports and Review of Literature
The lesion traditionally known as odontogenic keratocyst has been renamed by WHO in 2005, as “keratocystic odontogenic tumor” as it is more appropriate and reflects its potential for local, destructive behavior. It is a benign intraosseous neoplasm of jaw, which is unusual due to its characteristic histopathological and clinical features, including potentially aggressive behavior, high recurren...
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INTRODUCTION Keratocystic odontogenic tumours raise particular interest, because of their high recurrence rate and association with nevoid basal cell carcinoma syndrome. OBJECTIVE To analyze the clinical and histopathological features of all cases diagnosed as keratocystic odontogenic tumour in a Brazilian population. METHODS A total of 64 keratocystic odontogenic tumours, arising in forty-...
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Odontogenic keratocyst (OKC) is a common developmental odontogenic cyst affecting the maxillofacial region. Multiple OKCs are usually seen in association with nevoid basal cell carcinoma syndrome (NBCCS) but approximately 5% of patients with OKC have multiple cysts without concomitant syndromic presentation. This report represents a case of multiple OKCs in a non-syndromic patient.
متن کاملKeratocystic odontogenic tumor: a retrospective study of 183 cases.
In 2005, the WHO Working Group considered odontogenic keratocyst (OKC) to be a tumor and recommended the term keratocystic odontogenic tumor (KCOT), separating the lesion from the orthokeratinizing variant, which is now considered an odontogenic cyst. We analyzed the clinicopathological features of KCOTs encountered over a period of 28 years at Meikai University Hospital. The diagnosis was conf...
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OBJECTIVES PTCH, the human homologue of the Drosophila segment polarity gene, patched, has been identified as the gene responsible for nevoid basal cell carcinoma syndrome. The aim of this study was to investigate PTCH gene mutation in Chinese patients with nevoid basal cell carcinoma syndrome. MATERIALS AND METHODS DNA was isolated from both odontogenic keratocyst tissue and peripheral blood...
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